200 research outputs found

    Developing a Mobile Application‐Based Particle Image Velocimetry Tool for Enhanced Teaching and Learning in Fluid Mechanics: A Design‐Based Research Approach

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    A robust and intuitive understanding of fluid mechanics—the applied science of fluid motion—is foundational within many engineering disciplines, including aerospace, chemical, civil, mechanical, naval, and ocean engineering. In‐depth knowledge of fluid mechanics is critical to safe and economical design of engineering applications employed globally everyday, such as automobiles, aircraft, and sea craft, and to meeting global 21st century engineering challenges, such as developing renewable energy sources, providing access to clean water, managing the environmental nitrogen cycle, and improving urban infrastructure. Despite the fundamental nature of fluid mechanics within the broader undergraduate engineering curriculum, students often characterize courses in fluid mechanics as mathematically onerous, conceptually difficult, and aesthetically uninteresting; anecdotally, undergraduates may choose to opt‐out of fluids engineering‐related careers based on their early experiences in fluids courses. Therefore, the continued development of new frameworks for engineering instruction in fluid mechanics is needed. Toward that end, this paper introduces mobile instructional particle image velocimetry (mI‐PIV), a low‐cost, open‐source, mobile application‐based educational tool under development for smartphones and tablets running Android. The mobile application provides learners with both technological capability and guided instruction that enables them to visualize and experiment with authentic flow fields in real time. The mI‐PIV tool is designed to generate interest in and intuition about fluid flow and to improve understanding of mathematical concepts as they relate to fluid mechanics by providing opportunities for fluids‐related active engagement and discovery in both formal and informal learning contexts

    UC-Secure CRS Generation for SNARKs

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    Zero-knowledge SNARKs (zk-SNARKs) have recently found various applications in verifiable computation and blockchain applications (Zerocash), but unfortunately they rely on a common reference string (CRS) that has to be generated by a trusted party. A standard suggestion, pursued by Ben Sasson et al. [IEEE S&P, 2015], is to generate CRS via a multi-party protocol. We enhance their CRS-generation protocol to achieve UC-security. This allows to safely compose the CRS-generation protocol with the zk-SNARK in a black-box manner with the insurance that the security of the zk-SNARK is not influenced. Differently from the previous work, the new CRS-generation protocol also avoids the random oracle model which is typically not required by zk-SNARKs themselves. As a case study, we apply the protocol to the state-of-the-art zk-SNARK by Groth [EUROCRYPT, 2016]

    Molecular imaging of cell death in vivo by a novel small molecule probe

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    Apoptosis has a role in many medical disorders, therefore assessment of apoptosis in vivo can be highly useful for diagnosis, follow-up and evaluation of treatment efficacy. ApoSense is a novel technology, comprising low molecular-weight probes, specifically designed for imaging of cell death in vivo. In the current study we present targeting and imaging of cell death both in vitro and in vivo, utilizing NST-732, a member of the ApoSense family, comprising a fluorophore and a fluorine atom, for both fluorescent and future positron emission tomography (PET) studies using an 18F label, respectively. In vitro, NST-732 manifested selective and rapid accumulation within various cell types undergoing apoptosis. Its uptake was blocked by caspase inhibition, and occurred from the early stages of the apoptotic process, in parallel to binding of Annexin-V, caspase activation and alterations in mitochondrial membrane potential. In vivo, NST-732 manifested selective uptake into cells undergoing cell-death in several clinically-relevant models in rodents: (i) Cell-death induced in lymphoma by irradiation; (ii) Renal ischemia/reperfusion; (iii) Cerebral stroke. Uptake of NST-732 was well-correlated with histopathological assessment of cell-death. NST-732 therefore represents a novel class of small-molecule detectors of apoptosis, with potential useful applications in imaging of the cell death process both in vitro and in vivo

    Research on Teaching and Learning Mathematics at the Tertiary Level:State-of-the-art and Looking Ahead

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    This topical survey focuses on research in tertiary mathematics education, a field that has experienced considerable growth over the last 10 years. Drawing on the most recent journal publication as well as the latest advances from recent high quality conference proceedings, our review culls out the following five emergent areas of interest: mathematics teaching at the tertiary level; the role of mathematics in other disciplines; textbooks, assessment and students’ studying practices; transition to the tertiary level; and theoretical-methodological advances. We conclude the survey with a discussion of some potential ways forward for future research in this new and rapidly developing domain of inquiry

    Militarization and social development in the Third World

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    In this study we integrated the modernization and dependency theories of development to suggest the ways whereby militarization can affect development. We examined the effects of three components of militarization highlighted in these theories on the social development of ninety-two developing countries. Overall, our findings support the dependency theory's emphasis on the detrimental impact of international trade on disadvantaged nations. There is a significant negative correlation between arms import and social development. Arms export and indigenous spending are correlated with social development in the expected directions but their beta coefficients are not significant. The diverse ways these three aspects of militarization have been shown to affect social development help to explain some of the conflicting findings in the literature and point to the need to study these variables in their disaggregated form.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69141/2/10.1177_144078339503100105.pd

    Towards an Embodied Sociology of War

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    While sociology has historically not been a good interlocutor of war, this paper argues that the body has always known war, and that it is to the corporeal that we can turn in an attempt to develop a language to better speak of its myriad violences and its socially generative force. It argues that war is a crucible of social change that is prosecuted, lived and reproduced via the occupation and transformation of myriad bodies in numerous ways from exhilaration to mutilation. War and militarism need to be traced and analysed in terms of their fundamental, diverse and often brutal modes of embodied experience and apprehension. This paper thus invites sociology to extend its imaginative horizon to rethink the crucial and enduring social institution of war as a broad array of fundamentally embodied experiences, practices and regimes

    The Achene Mucilage Hydrated in Desert Dew Assists Seed Cells in Maintaining DNA Integrity: Adaptive Strategy of Desert Plant Artemisia sphaerocephala

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    Despite proposed ecological importance of mucilage in seed dispersal, germination and seedling establishment, little is known about the role of mucilage in seed pre-germination processes. Here we investigated the role of mucilage in assisting achene cells to repair DNA damage during dew deposition in the desert. Artemisia sphaerocephala achenes were first treated Îł-irradiation to induce DNA damage, and then they were repaired in situ in the desert dew. Dew deposition duration can be as long as 421 min in early mornings. Intact achenes absorbed more water than demucilaged achenes during dew deposition and also carried water for longer time following sunrise. After 4-d dew treatment, DNA damage of irradiated intact and demucilaged achenes was reduced to 24.38% and 46.84%, respectively. The irradiated intact achenes exhibited much higher DNA repair ratio than irradiated demucilaged achenes. Irradiated intact achenes showed an improved germination and decreased nonviable achenes after dew treatment, and significant differences in viability between the two types of achenes were detected after 1020 min of dew treatment. Achene mucilage presumably plays an ecologically important role in the life cycle of A. sphaerocephala by aiding DNA repair of achene cells in genomic-stressful habitats
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